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https://w.atwiki.jp/metalmetabo/pages/32.html
- visitors Development of network-based pathway definitions the need to analyze real metabolic networks nhahocotton.org.vn [PDF]BO Palsson, ND Price, JA Papin - Update, 2003 - nhahocotton.org.vn http //scholar.google.com/scholar?q=related RJrIZTi52eQJ scholar.google.com/ hl=ja as_sdt=2000 ... A recent article [1] addresses the important issue of network-based metabolic pathway analysis. ... References 1 Klamt, S. and Stelling, J. (2003) Two approaches for metabolic pathway analysis? Trends Biotechnol. 21, 64–69 2 Karp, PD et al. ... PathFinder reconstruction and dynamic visualization of metabolic pathways oxfordjournals.org [PDF]A Goesmann, M Haubrock, F Meyer, J … - …, 2002 - Oxford Univ Press http //scholar.google.com/scholar?q=related tN609hXVn9QJ scholar.google.com/ hl=ja as_sdt=2000 ... database. Nucleic Acids Res., 26, 43–45. Tohsato,Y., Matsuda,H. and Hashimoto,A.(2000) A multiple align- ment algorithm for metabolic pathway analysis using enzyme hierarchy. Proceedings, ISMB 2000. pp. 376–383. Wackett ... Toward metabolic phenomics analysis of genomic data using flux balances dss.go.th [PDF]CH Schilling, JS Edwards, BO … - Biotechnology progress, 1999 - Wiley Online Library http //scholar.google.com/scholar?q=related 5xFNmiGLuFoJ scholar.google.com/ hl=ja as_sdt=2000 ... This approach of metabolic pathway analysis accompanied with FBA techniques can allow one to assess the basic structural capabilities and fitness of an organism as a result of the pathways that are theoretically present within the cell. ... Robustness Analysis of the Escherichiacoli Metabolic Network dss.go.th [PDF]JS Edwards, BO Palsson - Biotechnology Progress, 2000 - interscience.wiley.com http //scholar.google.com/scholar?q=related F73ImcZpznMJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. Robustness Analysis of the Escherichia coli Metabolic Network Jeremy S.Edwards† and Bernhard O. Palsson* Department of Bioengineering, University of California-San Diego, La Jolla, California 92093-0412 Genomic ... FluxAnalyzer exploring structure, pathways, and flux distributions in metabolic networks on interactive flux maps oxfordjournals.org [PDF]S Klamt, J Stelling, M Ginkel, ED Gilles - Bioinformatics, 2003 - Oxford Univ Press http //scholar.google.com/scholar?q=related vOydM3d06iMJ scholar.google.com/ hl=ja as_sdt=2000 ... additionally reversibility and capacity restrictions for each reaction. Metabolic Pathway Analysis (MPA) searches for meaningful structural and functional units in metabolic networks. The two most promising, very similar ap- proaches ... Integrating cybernetic modeling with pathway analysis provides a dynamic, systems-level description of metabolic control JD Young, KL Henne, JA Morgan, AE … - Biotechnology and …, 2008 - interscience.wiley.com http //scholar.google.com/scholar?q=related SiQjLbrsCw4J scholar.google.com/ hl=ja as_sdt=2000 ... biochemical networks. Combining cybernetic control laws with concepts from metabolic pathway analysis has culminated in a sys- tematic strategy for constructing cybernetic models, which was previously lacking. The newly ... Exploring the pathway structure of metabolism decomposition into subnetworks and application to Mycoplasma pneumoniae oxfordjournals.org [PDF]S Schuster, T Pfeiffer, F Moldenhauer, I Koch, T … - …, 2002 - Oxford Univ Press http //scholar.google.com/scholar?q=related o1Qpi78HxmoJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. BIOINFORMATICS Vol. 18 no. 2 2002 Pages 351–361 Exploring the pathway structure of metabolism decomposition into subnetworks and application to Mycoplasma pneumoniae S. Schuster 1 , T. Pfeiffer 2 , F. Moldenhauer 1 , I. Koch 3 and T. Dandekar 4, 5 ... The complete genome sequence of the gastric pathogen Helicobacter pylori JF Tomb, O White, AR Kerlavage, RA Clayton, GG … - Nature, 1997 - nature.com http //scholar.google.com/scholar?q=related Eo36dy8hFLcJ scholar.google.com/ hl=ja as_sdt=2000 ... Top of page Metabolism. Metabolic pathway analysis of the H. pylori genome suggests the following features. H. pylori uses glucose as the only source of carbohydrate and the main source for substrate-level phosphorylation. ... Deriving phylogenetic trees from the similarity analysis of metabolic pathways oxfordjournals.org [PDF]M Heymans, AK Singh - Bioinformatics, 2003 - Oxford Univ Press http //scholar.google.com/scholar?q=related Y2vvexN5fz8J scholar.google.com/ hl=ja as_sdt=2000 Page 1. BIOINFORMATICS Vol. 19 Suppl. 1 2003, pages i138–i146 DOI 10.1093/bioinformatics/btg1018 Deriving phylogenetic trees from the similarity analysis of metabolic pathways Maureen Heymans and Ambuj K. Singh ∗ ... Treatment of multifunctional enzymes in metabolic pathway analysis S Schuster, I Zevedei-Oancea - Biophysical chemistry, 2002 - Elsevier http //scholar.google.com/scholar?q=related G_O7SiZhvKsJ scholar.google.com/ hl=ja as_sdt=2000 In metabolic pathway analysis, it should be considered that many enzymes operate with low specificity (eg nucleoside diphosphokinase, uridine kinase, transketolase, aldolase), so that various substrates and products can be converted. Here, we analyze the effect of ...
https://w.atwiki.jp/hideo/pages/7.html
How-To build Linux home server The page is the record to build my home server. Basically the server is based on Redhat Linux 9. Hard WareUPS Hard Ware RAID-1 (Mirroring) [HotSwap?] (Spare Disk?) NIC 5 Inch Front Bay Soft WareFirewall (Filtering) IP Masquerade sshd DNS SMBd(Samba) HTTPD(APATCH) MTA NTPD(xntp) Serial connection setup VPN postgreSQL NFSD Dynamic DNS(ddclient) Proxy(Squid) syslogd, klogd Line Printer Daemon(printcap, filter) FTPd(wu-ftp) ConcernWireless LAN Security 多くのサイトがinetd を tcpserver で置き換えつつあります。以下にいくつかの理由をあげます: Execution NoteInstall RedHat Linux 9 by FTP Think about the folowing things. http //www.linux.or.jp/JF/JFdocs/Security-Quickstart-Redhat-HOWTO/ Update to the Linux kernel 2.6 http //homepage1.nifty.com/mcn/linux/topic1.5/kernel_rebuild.2.6.htm Hard Ware UPS http //en.tldp.org/HOWTO/UPS-HOWTO/ Hard Ware RAID-1 (Mirroring) [HotSwap?] (Spare Disk?) http //www.accusys.com.tw/ http //www.infortrend.com/ http //www.raidon.com.tw/ http //www.promise.com/ http //www.maxtronic.com.tw/ http //www.hans.or.jp/MALL/able/parts/raid-1.html I have Iwill SIDE Pro66 that uses HighPoint HPT366.http //www.highpoint-tech.com/370drivers_down.htm NIC 802.11b 802.11g Wireless LAN (PLANEX GW-DS54G http //www.planex.co.jp/product/bwave/gwds54g.shtml) (PLANEX GW-DS54G http //www.planex.net/product/bwave/gwds54g.shtml)Linux Driver for the 802.11g Prism GT / Prism Duette / Prism Indigo Chipsets http //prism54.org A Linux Wireless Access Point HOWTO http //oob.freeshell.org/nzwireless/LWAP-HOWTO.html Wireless LAN resources for Linux http //www.hpl.hp.com/personal/Jean_Tourrilhes/Linux/Wireless.html 100M Ethernet 1 ----Global 5 Inch Front Bay 2 for RAID-1 (Do not need CD-ROM drive. We can do FTP based install.) Soft Ware Firewall (Filtering) IP Masquerade edit /etc/sysctl.conf sshd DNS bind djbdns http //cr.yp.to/djbdns.html SMBd(Samba) HTTPD(APATCH) MTA qmail http //www.qmail.org/ NTPD(xntp) http //www.ntp.org/index.html Serial connection setup VPN postgreSQL NFSD Dynamic DNS(ddclient) Proxy(Squid) syslogd, klogd Line Printer Daemon(printcap, filter) FTPd(wu-ftp) Concern Wireless LAN Security Allied telesis http //www.allied-telesis.co.jp/products/list/wireless/knowl.html#sec Data EncriptionWEP Wireless tools for Linux supports http //www.hpl.hp.com/personal/Jean_Tourrilhes/Linux/Tools.html WPA http //hostap.epitest.fi/cgi-bin/viewcvs.cgi/hostap/wpa_supplicant/ Access Control prism54 driver support MAC Address filtering 多くのサイトがinetd を tcpserver で置き換えつつあります。以下にいくつかの理由をあげます: inetd は高負荷では信頼性が低下します。 1分間に「多過ぎる」接続要求を受けとると、10分間サービスを中断します。 inetd の資源管理は有効ではありません。よく使われるサービスを動かしていると、いとも簡単に メモリを使い切る でしょう。 inetd では活動が集中的に起きると、トラブルとなります。その listen() バックログ は通常 5 か 10 であり、大きくすることはできません。 Execution Note Install RedHat Linux 9 by FTP Create bootdisk and driver disk and get FTP information. Install RedHat Linux 9, choose modules. Set high secure mode. Create new users (add sudoer list) # adduser hideo # password hideo #TYPE password # cp /etc/sudoers{,.20040410} # visudo Use new sudoed users to make configuration Settinup /etc/XF86Config sudo cp /etc/XF86Config{,.20040410} sudo vi /etc/XF86Config Change keyboard setting sudo cp /lib/kbd/keymaps/i386/qwerty/{us.map.gz,us_swap_ctrl_capsLock.map.gz} gunzip /lib/kbd/keymaps/i386/qwerty/us_swap_ctrl_capsLock.map.gz sudo vi /lib/kbd/keymaps/i386/qwerty/us_swap_ctrl_capsLock.map #Swap 28 and 59 sudo gzip /lib/kbd/keymaps/i386/qwerty/us_swap_ctrl_capsLock.map sudo cp /etc/sysconfig/keyboard{,.20040410} sudo vi /etc/sysconfig/keyboard #use new key map us_swap_ctrl_capsLock Drop run level 3 services /etc/rc.d/rc3.d/S05kudzu - ../init.d/kudzu /etc/rc.d/rc3.d/S08iptables - ../init.d/iptables DELETE /etc/rc.d/rc3.d/S09isdn - ../init.d/isdn /etc/rc.d/rc3.d/S10network - ../init.d/network /etc/rc.d/rc3.d/S12syslog - ../init.d/syslog DELETE /etc/rc.d/rc3.d/S13portmap - ../init.d/portmap DELETE /etc/rc.d/rc3.d/S14nfslock - ../init.d/nfslock /etc/rc.d/rc3.d/S17keytable - ../init.d/keytable /etc/rc.d/rc3.d/S20random - ../init.d/random DELETE /etc/rc.d/rc3.d/S24pcmcia - ../init.d/pcmcia DELETE /etc/rc.d/rc3.d/S25netfs - ../init.d/netfs /etc/rc.d/rc3.d/S26apmd - ../init.d/apmd DELETE /etc/rc.d/rc3.d/S28autofs - ../init.d/autofs /etc/rc.d/rc3.d/S55sshd - ../init.d/sshd /etc/rc.d/rc3.d/S56rawdevices - ../init.d/rawdevices DELETE /etc/rc.d/rc3.d/S56xinetd - ../init.d/xinetd DELETE /etc/rc.d/rc3.d/S80sendmail - ../init.d/sendmail /etc/rc.d/rc3.d/S85gpm - ../init.d/gpm /etc/rc.d/rc3.d/S90canna - ../init.d/canna /etc/rc.d/rc3.d/S90crond - ../init.d/crond DELETE /etc/rc.d/rc3.d/S90cups - ../init.d/cups /etc/rc.d/rc3.d/S90FreeWnn - ../init.d/FreeWnn /etc/rc.d/rc3.d/S90xfs - ../init.d/xfs /etc/rc.d/rc3.d/S95anacron - ../init.d/anacron /etc/rc.d/rc3.d/S95atd - ../init.d/atd /etc/rc.d/rc3.d/S97rhnsd - ../init.d/rhnsd /etc/rc.d/rc3.d/S99local - ../rc.local sudo rm /etc/rc.d/rc3.d/S13portmap sudo rm /etc/rc.d/rc3.d/S14nfslock sudo rm /etc/rc.d/rc3.d/S24pcmcia sudo rm /etc/rc.d/rc3.d/S25netfs sudo rm /etc/rc.d/rc3.d/S28autofs sudo rm /etc/rc.d/rc3.d/S56 sudo rm /etc/rc.d/rc3.d/S56xinetd sudo rm /etc/rc.d/rc3.d/S80sendmail sudo rm /etc/rc.d/rc3.d/S90cups mkdir usr mkdir usr/TARBALL mkdir usr/src mkdir usr/lib mkdir usr/bin mv ncftp-3.1.7-src.tar.gz ./usr/TARBALL/ down load prism54 and patch on the latest Kernel compile new kernel make mrproper make menuconfig (follow the prism54 README) (if you comple the libraries, that you need to boot) make dep make clean make bzImage make modules sudo make modules_install sudo cp arch/i386/boot/bzImage /boot/vmlinuz-2.4.25 sudo cp System.map /boot/System.map-2.4.25 mkinitrd /boot/initrd-2.4.25.img 2.4.25 vi /etc/grub.conf === Add new entry for new kernel Wired Networking Setup sudo mv /etc/sysctl.conf{,.20040413} sudo vi /etc/sysctl.conf # Controls source route verification net.ipv4.conf.default.rp_filter = 1 sudo vi /etc/sysconfig/network-scripts/ifcfg-eth0 (DHCP) sudo vi /etc/sysconfig/network-scripts/ifcfg-eth1 (STATIC) sudo cp /etc/sysconfig/iptables{,.20040413} sudo vi /etc/sysconfig/iptables Wireless Networking Setup sudo vi /etc/sysconfig/network-scripts/ifcfg-eth2 (STATIC) sudo vi /etc/rc.d/local (ifup eth2) NOTE eth2 is BOOT=NO The eth2 is up in S99local. I do not know exactreason why but ON_BOOT does not work. It sesms like hotplug does notwork because it fails upload firm waire accrding to the error message. sudo cp ./WLANDCB.arm /usr/lib/hotplug/firmware/isl3890 wget http //prism54.org/~hvr/firmware.agent sudo cp ./firmware.agent /etc/hotplug/ sudo chmod 755 /etc/hotplug/firmware.agent ifup eth2 iwconfig eth2 essid "????" iwconfig eth2 made Master iwconfig eth2 off Compile wireless tools sudo mv iwgetid{,.20040421} sudo mv iwspy{,.20040421} sudo mv iwevent{,.20040421} sudo mv iwpriv{,.20040421} sudo mv iwlist{,.20040421} sudo mv iwconfig{,.20040421} sudo cp ~hideo/usr/src/wireless_tools.26/iwgetid . sudo cp ~hideo/usr/src/wireless_tools.26/iwevent . sudo cp ~hideo/usr/src/wireless_tools.26/iwpriv . sudo cp ~hideo/usr/src/wireless_tools.26/iwlist . sudo cp ~hideo/usr/src/wireless_tools.26/iwconfig .
https://w.atwiki.jp/youge_wiki/pages/23.html
種族 GOBLINS ”Grabbit! Run! Eeek!” "ツカメ!ハシレ!ィイイイ!" Goblinsチームを運営するのには、大概緑皮の狂人と同じぐらい 戦いにキ■■イで熱心であるような特別な種類のコーチングが必要です! Goblinsは、抜け目なく戦い、めったにそれをやめたりしません。 彼らは、滅多打ちにされた後ですら、より多くの仕返しのために 再び現れますが、もっと簡単な獲物を選び、尖った歯が装着された ワイルドでぶっ飛んだ発明を持ち出すのを好みます。 ですので、Goblinsチームで奇妙な装置をたくさん見るのは、 珍しいことでありません。チェーン付きスパイクボールや ChainSaw、噂の恐るべきホッピングなどのように! BloodBowl DarkElevesEdition ”StrategyGuide”より引用 GOBLINS Salary 40,000GP Value 40 Status Skill Categories MA AG ST AV Mutation Strength General Agility Passing 6 2 3 7 NO Double Double Normal Double Skills no They’re small, they’re fragile and seem unable to handle the ball if, that is, they ever get near it. In short (no pun intended!), they are hopeless individually. But, when you line up a few of them, the odds can change to your advantage. At first glance, a Goblin seems cut out for running between opponents’ legs to score touchdown after touchdown while the crowd cheers them on… Dream on, they are not Wood Elves! Goblins have an average Agility Value (AG 3), so there is a chance that they can dash right through enemy Tackle Zones (one chance in three to fail, and at least one Re-roll dice thanks to the Dodge skill). But as the Dodge skill only works once per turn, so don’t push your luck by attempting to break through a long string of tackle zones, unless you have a team re-roll dice in reserve too. TROLLS Salary110,000GP Value 110 Status Skill Categories MA AG ST AV Mutation Strength General Agility Passing 4 1 5 9 No Normal Double Double Double Skills Always Hungry,Loner,Mighty Blow,Really Stupid,Regeneretion,Throw Team-mate Both Trolls are of vital importance to the Goblin team. They’re the ones who provide all the power and also enable you to set up Goblin Throwers (see box). Unfortunately, Trolls are certainly the weakest of all the Big Guys in the game, but they’re also the cheapest, barely the same price as a Wood Elf Wardancer! Their raw strength is impressive, but without the Block skill it’s easy for a well-assisted opponent (or one with the Dauntless skill) to knock them down. Fortunately, their natural ability to Regenerate and Armour value of 9 make them almost invincible. Their main flaw is their immeasurable stupidity and you absolutely need to keep a Goblin standing close by with a really sharp pointy stick to prod them when needs be. POGOR Salary 40,000GP Value 40 Status Skill Categories MA AG ST AV Mutation Strength General Agility Passing 7 3 2 7 NO Normal Double Double Double Skills Secret Weapon,Dodge,Dirty Player,Leap,Very Long Leg,Stunty One of the more unusual players even by Blood Bowl standards. The combination of Leap, Dodge and Stunty skills make him a very mobile player and a Pogoer can perform wonders when he has the ball. He has a Movement value of 7, which gives them the little extra that is often enough to get away from those who are chasing him. If you protect this player, he should go up a level by scoring touchdowns or fouling since the Pogoer also benefits from the Dirty Player skill, if ever the dice permit always improve their Movement ability. Otherwise, stick with the basics and give them Block as they will most likely be the ones all alone in the enemy half. LOONEY Salary 40,000GP Value 40 Status Skill Categories MA AG ST AV Mutation Strength General Agility Passing 6 3 2 7 NO Double Double Normal Double Skills Secret Weapon,Stunty,No Hands,Chain Saw These are one of the most lethal weapons in the Goblin coach’s arsenal. The Chainsaw wielding Goblin is not only a good offensive player but can also hold their own in defence because opponents will hesitate to engage them if they don’t have the Block skill. As they are a primary target for opposing teams, try to keep your Looney out of big huddles and use them against isolated enemy players but remember to always provide them with support. You don’t roll Block dice with the looney, it’s straight to the Armour roll! And the Chainsaw adds a bonus to the Armour rolls too, but does not provide one for the Injury dice. Sadly there’s no SPPs for injuring players with a chainsaw, so there is very little chance that the player will evolve. FANATIC Salary 70,000GP Value 70 Status Skill Categories MA AG ST AV Mutation Strength General Agility Passing 3 3 7 7 NO Normal Double Double Double Skills Secret Weapon,Ball Chain,No Hands,Stunty Fanatics are probably the most entertaining players on the Blood Bowl pitch and also available at a bargain price. Using a Fanatic can be a big disaster or a miracle. Use them well because they advance in a random direction so it’s difficult to plan their movement, however once they start, take the risk and Go For It! to break through enemy lines. You won’t have that many opportunities, so exploit each one for what it’s worth. Sometimes it is better to keep a Fanatic in reserve and wait for the right time to send them into the other team. The main problem will be protecting the Fanatic without risking your own players being hit on the back of the head and taken out. If he miraculously goes up a level, don’t hesitate to choose Mighty Blow or Sprint, or if lucky, an additional point of Movement. STARPLAYER RIPPER Salary 430,000GP Value 0 Status Skill Categories MA AG ST AV Mutation Strength General Agility Passing 6 3 6 10 Normal Normal Normal Double Double Skills Mighty Blow,Loner,Block,Thcik Skull,Throw Team-mate Morg N Thorg Salary 430,000GP Value 0 Status Skill Categories MA AG ST AV Mutation Strength General Agility Passing 6 3 6 10 Normal Normal Normal Double Double Skills Mighty Blow,Loner,Block,Thcik Skull,Throw Team-mate
https://w.atwiki.jp/the_wanderer/pages/8.html
FAQ TIPS FOR CHANNEL2 NEW ZEALAND BASICS 1. What is CHANNEL2 NEW ZEALAND ? 2. Is this place free? 3. Is this place dangerous? 4. How am I supposed to trust you? 5. Are there any rules? HOW TO~ 6. How do I build a thread? 7. How do I respond to a thread? 8. How can I volunteer to become a staff member? 9. How can I send a banner or top picture for the site,or an advertisement for my site? 1. What is CHANNEL2 NEW ZEALAND ? CHANNEL2 NEW ZEALAND is New Zealand s largest anonymous thread-float BBS community,with boards about almost everything. 2. Is this place free? Yes, it is, since being a teenager, I m not skilled enough to take money from people like you wwwww ok wwwww, and I used only free CGIs and server space so I don t need any money to administer this site. 3. Is this place dangerous? This site is not intended to be dangerous in any way. However, the safety of this site will depend on what kind of people are using it.Hiroyuki Nishimura, administrator of2ちゃんねる(2CHANNNERU, the real CHANNEL2),said that 2CHANNNERU is hard to use for people who can t tell lies from truth ,and that pretty much sums it up. 4. How am I supposed to trust you? Well, as I ve said before, I m only a teenager. Also, I ve posted my mail address, and I m Japanese (Japanese men take pride in the fact that they are rather honest). Isn t that enough? Maybe not orz... Still, I intend to do no harm to anybody. 5. Are there any rules? Yes, but not many. There are local rules for each board, and you are expected to act sensibly, but otherwise, you re sweet as. 6. How do I build a thread? 1. Go to the bottom of the board. 2. In the first box, type in the title of the thread. 3. In the second box, type in your handlename. Since this is an anonymous BBS,you don t need to have a handlename, just if you want to. Also,I d like to note that every board has a different name that shows up if you leave the handlename box blank. 4. In the third box, type in your mail address (again, this is optional.You can leave it blank, but there are certain commands that are activated by typing certain words in to this box). 5.In the last box, type in the text, push the button, and presto! A new thread is born! 7. How do I respond to a thread? 1. Go to the bottom of the thread you want to respond to. 2. Type in your handlename in the first box (optional). 3. Type in your mail address in the second box (optional). 4. Type in the text in the next box and push the button. 8. How can I volunteer to become a staff member? 9. How can I send a banner or top picture for the site or a board,or an advertisement for my site? Contact me via e-mail the_wanderer@excite.co.jp TIPS FOR CHANNEL2 NEW ZEALAND BASICS 1. age sage If you type in the mail address box sage when you respond to a thread, this will make the thread go down the thread list one space. If you type in age when you respond to a thread, it will go to the top of the thread list. 2. The anchor When you want to respond to a certain person in a thread, you can type in response number of that person in the text box, and a link to that response will be in the response you sent. 3. The trip You can use a trip to identify yourself and prevent anybody from using your handlename. All you need to do is type in the handlename box handlename #password of your choice something like this will show up next to your handlename ◆NdKrQ0UM If somebody copies this in to his handlename box, a ◇ will appear instead of the ◆,so it will verify that he is an imposter. OK? 4. Linking You can not use HTML in any of the boards. However, if you paste a URL in the text box, a link will form automaticaly.
https://w.atwiki.jp/metalmetabo/pages/26.html
- visitors Combining pathway analysis with flux balance analysis for the comprehensive study of metabolic systems slu.edu [PDF]… JS Edwards, D Letscher, BØ Palsson - Biotechnology and …, 2000 - interscience.wiley.com http //scholar.google.com/scholar?q=related HtFdZ3DFTgMJ scholar.google.com/ hl=ja as_sdt=2000 ... dimensional space. From metabolic pathway analysis, the edges of the high-dimensional flux cone are vectors that correspond to sys- temically defined “extreme pathways” spanning the ca- pabilities of the system. The addition ... Metabolic pathway analysis of yeast strengthens the bridge between transcriptomics and metabolic networks T Çakir, B Kirdar, KÖ Ülgen - Biotechnology and …, 2004 - Wiley Online Library http //scholar.google.com/scholar?q=related cUtrabByB40J scholar.google.com/ hl=ja as_sdt=2000 Abstract Central carbon metabolism of the yeast Saccha- romyces cerevisiae was analyzed using metabolic pathway analysis tools. Elementary flux modes for three substrates (glucose, galactose, and ethanol) were determined using the catabolic reactions ... Metabolic pathway analysis for rational design of L-methionine production by Escherichia coli and Corynebacterium glutamicum JO Krömer, C Wittmann, H Schröder, E Heinzle - Metabolic engineering, 2006 - Elsevier http //scholar.google.com/scholar?q=related KSxlsQoF_oIJ scholar.google.com/ hl=ja as_sdt=2000 Metabolic pathway analysis was carried out to predict the metabolic potential of Corynebacterium glutamicum and Escherichia coli for the production of L-methionine. Based on detailed stoichiometric models for these organisms, this allowed the calculation of the theoretically optimal ... The genome-scale metabolic extreme pathway structure in Haemophilus influenzae shows significant network redundancy JA Papin, ND Price, JS Edwards, BØ … - Journal of theoretical …, 2002 - Elsevier http //scholar.google.com/scholar?q=related KrUkw9kndisJ scholar.google.com/ hl=ja as_sdt=2000 ... 229–248. Abstract | PDF (428 K) | View Record in Scopus | Cited By in Scopus (198). 19. CHSCHILLING, S. SCHUSTER, BO PALSSON and R. HEINRICH, Metabolic pathway analysis basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. ... Potential drug targets in Mycobacterium tuberculosis through metabolic pathway analysis psu.edu [PDF]S Anishetty, M Pulimi, G Pennathur - Computational Biology and …, 2005 - Elsevier http //scholar.google.com/scholar?q=related hEJbAmAPhwkJ scholar.google.com/ hl=ja as_sdt=2000 The emergence of multidrug resistant varieties of Mycobacterium tuberculosis has led to a search for novel drug targets. We have performed an insilico comparative analysis of metabolic pathways of the host Homo sapiens and the pathogen M. tuberculosis. Enzymes from the ... In silico metabolic pathway analysis and design succinic acid production by metabolically engineered Escherichia coli as an example jsbi.org [PDF]SY Lee, SH Hong, SY Moon - GENOME INFORMATICS SERIES, 2002 - jsbi.org http //scholar.google.com/scholar?q=related 6Ehoy39R1HUJ scholar.google.com/ hl=ja as_sdt=2000 Abstract The intracellular metabolic fluxes can be calculated by metabolic flux analysis, which uses a stoichiometric model for the intracellular reactions along with mass balances around the intra- cellular metabolites. In this study, we have constructed in silico metabolic pathway ... Determination of redundancy and systems properties of the metabolic network of Helicobacter pylori using genome-scale extreme pathway analysis cshlp.org [HTML]ND Price, JA Papin, BØ Palsson - Genome Research, 2002 - genome.cshlp.org http //scholar.google.com/scholar?q=related hyQpOmehsTYJ scholar.google.com/ hl=ja as_sdt=2000 Metabolic pathway analysis in trypanosomes and malaria parasites. nih.gov [PDF]AH Fairlamb - Philosophical Transactions of the Royal Society B …, 2002 - ncbi.nlm.nih.gov http //scholar.google.com/scholar?q=related x44FtcJTlQwJ scholar.google.com/ hl=ja as_sdt=2000 Identification of novel drug targets is required for the development of new classes of drugs to overcome drug resistance and replace less efficacious treatments. In theory, knowledge of the entire genome of a pathogen identifies every potential drug target in any given microbe. ... A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks uni-erlangen.de [PDF]S Schuster, DA Fell, T Dandekar - Nature biotechnology, 2000 - nature.com http //scholar.google.com/scholar?q=related 4GmcRTKIXlwJ scholar.google.com/ hl=ja as_sdt=2000 ... Trends Biotechnol. 17, 53–60(1999). | Article | PubMed | ISI | ChemPort |; Schilling, CH, Schuster, S., Palsson, BO Heinrich R. Metabolic pathway analysis basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. 15, 296–303 (1999). ...
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- visitors The small world inside large metabolic networks royalsocietypublishing.org [PDF]A Wagner, DA Fell - … of the Royal Society of London …, 2001 - rspb.royalsocietypublishing.org http //scholar.google.com/scholar?q=related RzgGd87o6owJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. doi 10.1098/rspb.2001.1711 , 1803-1810 268 2001 Proc. R. Soc. Lond. B Andreas Wagner and David A. Fell The small world inside large metabolic networks References http //rspb.royalsocietypublishing.org/content/268/1478/1803#related-urls Article cited in ... In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data vcu.edu [PDF]JS Edwards, RU Ibarra, BO Palsson - Nature biotechnology, 2001 - nature.com http //scholar.google.com/scholar?q=related E0x6EPMqz7kJ scholar.google.com/ hl=ja as_sdt=2000 ... J. Theor. Biol. 203, 249–83 (2000). | Article | PubMed | ISI | ChemPort |; Schilling, CH, Schuster, S., Palsson, BO Heinrich, R. Metabolic pathway analysis basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. 15, 296–303 (1999). ... The small world of metabolism stanford.edu [PDF]DA Fell, A Wagner - Nature Biotechnology, 2000 - nature.com http //scholar.google.com/scholar?q=related vJDOQbOxaVoJ scholar.google.com/ hl=ja as_sdt=2000 ... propositions. Top of page References. Schilling, CH, Schuster, S., Palsson, BO Heinrich, R. Metabolic pathway analysis basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. 15, 296–303 (1999). ... Metabolic pathways in the post-genome era psu.edu [PDF]JA Papin, ND Price, SJ Wiback, DA Fell, BO … - Trends in Biochemical …, 2003 - Elsevier http //scholar.google.com/scholar?q=related yCUSHfucTk8J scholar.google.com/ hl=ja as_sdt=2000 ... All possible flux distributions of a metabolic network lie within the 'cone' circumscribed by the pathways. View Within Article. 1. History of network-based metabolic pathway analyses. Network-based metabolic pathway analysis has a relatively short history. ... The Escherichia coli MG1655 in silico metabolic genotype its definition, characteristics, and capabilities pnas.org [HTML]JS Edwards, BO Palsson - … of Sciences of the United States …, 2000 - National Acad Sciences http //scholar.google.com/scholar?q=related ylmoiEQjy08J scholar.google.com/ hl=ja as_sdt=2000 ... These methods include approaches such as metabolic control analysis (3, 4), flux balance analysis (FBA) (5–7), metabolic pathway analysis (8–11, 69), cybernetic modeling (12), biochemical systems theory (13), temporal decomposition (14), and so on. ... Analysis of metabolic capabilities using singular value decomposition of extreme pathway matrices nih.gov [HTML]ND Price, JL Reed, JA Papin, I Famili, BO Palsson - Biophysical journal, 2003 - Elsevier http //scholar.google.com/scholar?q=related vBbGDsA7avcJ scholar.google.com/ hl=ja as_sdt=2000 Phylogenetic analysis based on genome-scale metabolic pathway reaction content silicobio.com [PDF]SH Hong, TY Kim, SY Lee - Applied microbiology and biotechnology, 2004 - Springer http //scholar.google.com/scholar?q=related 2MW2dxoUfOIJ scholar.google.com/ hl=ja as_sdt=2000 Page 1. Appl Microbiol Biotechnol (2004) 65 203–210 DOI 10.1007/s00253-004-1641-3 GENOMICS AND PROTEOMICS SH Hong . TY Kim . SY Lee Phylogenetic analysis based on genome-scale metabolic pathway reaction content ... Extreme pathway lengths and reaction participation in genome-scale metabolic networks cshlp.org [HTML]JA Papin, ND Price, BØ Palsson - Genome research, 2002 - genome.cshlp.org http //scholar.google.com/scholar?q=related o1ZwGAWEzSUJ scholar.google.com/ hl=ja as_sdt=2000 ... Schilling CH,; Schuster S.,; Palsson BO,; Heinrich R. (1999) Metabolic pathway analysis Basic concepts and scientific applications in the post-genomic era. Biotech. Prog. 15 296–303. ... Flux coupling analysis of genome-scale metabolic network reconstructions cshlp.org [HTML]AP Burgard, EV Nikolaev, CH Schilling, CD … - Genome …, 2004 - genome.cshlp.org http //scholar.google.com/scholar?q=related IXLhT3n9KwQJ scholar.google.com/ hl=ja as_sdt=2000 Metabolic modeling of microbial strains in silico ru.nl [PDF]MW Covert, CH Schilling, I Famili, JS Edwards, … - Trends in Biochemical …, 2001 - Elsevier http //scholar.google.com/scholar?q=related pjh6sWp3MRMJ scholar.google.com/ hl=ja as_sdt=2000 ... References. Schilling, CH et al., Metabolic pathway analysis basic concepts and scientific applications in the post-genomic era. Biotechnol. Prog. 15, pp. 296–303. Schilling, CH et al., Towards metabolic phenomics analysis of genomic data using flux balances. Biotechnol. ...
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Ace Attorney Investigations Miles Edgeworth Preview for the Nintendo DS from 1UP.comhttp //www.1up.com/do/previewPage?cId=3177783 p=39 sec=PREVIEWS 02/02/2010 1UP Mr. Eshiro, you re the producer on Ace Attorney Investigations, but could you tell us a little more about your role in the game s development?1UP:江城さんは逆転検事のプロデューサーですが、もうちょっとこのゲームでの役割について教えてください。Motohide Eshiro I started as co-producer on the second and third Ace Attorney games, but this is my first time in the series as full producer. Mostly, I look over the overall product schedule and budget. I make sure everything s coming in on time -- things like that.江城元秀:逆転裁判との関わりは、DS版逆転裁判2と3の共同プロデューサーとしての役割が始まりですが、これはプロデューサーとしての初めての仕事でもありました。大まかには、私は全てのスケジュールと予算・経費を統括します。全てが予定通りに動くかを確認します。Another big part of my job is focusing on the overall quality of the game. While the director focuses on specific aspects -- fine-tuning the small details -- my job is more to look at the big picture. To make sure that everything fits in well with whole concept. I look at it like the average user and ask myself, Will the player enjoy this? 他の大きな仕事としては、ゲームの全ての質に焦点を当てています。ディレクターがある局面――細かい部分の微調整――に集中している時、私の仕事は全体を見ることです。全ての事象が、全体と調和しているかの確認です。私は1ユーザーとしてゲームを見て、私自身に確認します。「プレイヤーはこれを楽しいと思うだろうか?」And of course, doing promotion for the game, like traveling abroad to give interviews.そしてもちろん、ゲームの宣伝もします。海外に出向いてインタビューを受けたり。1UP Your current position sounds very different from your previous role as director on Shadow of Rome and Onimusha...1UP:あなたの現在の仕事は、以前のSHADOW OF ROMEや鬼武者のディレクターとしての役割とずいぶん異なるようですが。ME Yeah, Ace Attorney is a very different type of game, but I really wasn t thinking of it as something completely different. During my school days, I used to play a lot of PC-based text adventures. I really loved those back then, and I ve always been a huge fan of adventure games.江城:ええ、逆転裁判はゲームとしては異なるタイプですが、私は完全に異なるものとは思っていません。私は学生時代、PCでテキストアドベンチャーを多くプレイしたものです。私はそういうゲームが好きで、アドベンチャーゲームの大ファンでした。When I was a director, I was able to make action games like Onimusha and Shadow of Rome, but I just didn t have the opportunity to make my own adventure game. But when I switched roles to producer on Ace Attorney, I finally got the chance to make the types of games I loved playing when I was younger.私はディレクターとして、アクションゲームの鬼武者とSHADOW OF ROMEを制作しましたが、アドベンチャーゲームを創る機会はありませんでした。しかし逆転裁判のプロデューサーになって、とうとうアドベンチャーゲームの制作に関われることになったのです。1UP Do you think your time working with such action heavy games has changed the way you approached Ace Attorney Investigations?1UP:そのようなアクションゲームの仕事を制作していた時から比べ、逆転検事へのアプローチには変化がありましたか?ME Definitely, there s been some influence. Of course, in text-based games there s always some level of interactivity. But working in action games, I had firsthand experience in how to lay out a scene. For example, if you ve got a character moving somewhere, the background has to scroll and move smoothly.江城:確かに、少しは影響がありました、もちろん、テキストベースのゲームでは、常にそれなりの会話があります。しかしアクションゲームの制作では、私はシーン毎のレイアウトをどうするかといったことを経験しました。例えば、キャラクターをどこかに動かす時、背景はなめらかにスクロールしなければなりません。I think I was able to transfer some of that experience into Ace Attorney Investigations. When you move Edgeworth around, you re not going to run into weird scrolling issues; you re not going to see awkward movements, or things like that, and I attribute that to my action game experience.そういった経験を、逆転検事に生かすことができたと思います。あなたがプレイした時、御剣を動かしても妙なスクロールを見たり、ぎこちない動きを見たりすることはないでしょう。そういったことは、アクションゲームの制作による経験からだと考えています。1UP Speaking of adventure games, over the past few years in America, we ve seen a bit of a revival of that genre with games like Sam Max and Monkey Island. Do those come to Japan at all?1UP:アドベンチャーゲームについてですが、アメリカでは過去、Sam MaxやMonkey Islandのようなゲームがリバイバルしています。日本ではどうですか?ME I don t think they do. But when I think about PC adventure games, I think about the really old titles. Of course, Myst was a popular title everywhere, but I really enjoyed Mystery House. I can t think of other specific titles right at the moment, but just really old games, or games like Portopia, which never came out outside Japan. I really haven t tried out any recent adventure games. Even in Japan, they ve never remade some of my favorite titles, like Snatcher.江城:日本ではなかったと思います。しかし、私がPCのアドベンチャーゲームについて考える時、私は本当に古いタイトルについて思いを巡らせます。もちろん、Mystは有名ですが、私はMystery Houseが楽しかった。他の具体的なタイトルは思い出せないけれど、日本以外では発売されなかったポートピア連続殺人事件が好きです。私は最近のアドベンチャーゲームはプレイしていません。日本でさえ、スナッチャーのような私の好きなゲームのいくつかはリメイクされていません。With Mystery House, that was a game I played when I was still in college -- but it only came out in English. I didn t immediately understand half of what was written; maybe just a word like take, and then I d have to look up the rest to understand what I was able to take. So I d play along with a dictionary; it was almost like studying, but a lot more fun.Mystery Houseは、私が大学生のころにプレイしたゲームでした――しかし英語版しかありませんでした。私は書いてあることの半分も理解できませんでした。「take」というワードがあっても、何が取得できるのか、調べなくてはなりませんでした。そのため、私は辞書を片手にプレイしていました、それはまるで勉強みたいでしたが、楽しみでもありました。But Portopia is a game that s really stuck with me over the years. Are you ok with spoilers?しかし、ポートピア連続殺人事件は長年楽しく遊べたゲームです。ネタバレは大丈夫?1UP I think the game s old enough that that s ok.1UP:昔のゲームだから大丈夫。ME Well, the detective that you work with, the big twist at the end is that he s the criminal. You re supposed to be working closely with this guy, and you don t find out till much later that he s actually the one behind it all. And that highlights one of the most important aspects of adventure and text games for me the turnaround point.江城:じゃあ‥‥一緒に行動する刑事が犯人という、ものすごい結末なんです。彼とずっと一緒に行動していくんですが、最後の最後にならないと真相はわかりません。テキストアドベンチャーゲームにおいて最も重要なことのひとつ、転換点を私に見せてくれたのです。In the Ace Attorney series you always have these surprising twists, sometimes two or three times in one case. You just never know what to expect. That s what keeps adventure games interesting for me.逆転シリーズにおいては、1つの事件の中で、2つや3つのこういった驚くべき逆転劇を見ることになります。そしてあなたは何が起こるか全く解らない。それが私にとって、アドベンチャーゲームの面白さです。1UP It s obviously a very different type of game, but another popular adventure game I m sure you ve spent some time with is Professor Layton.1UP:明らかに異なるタイプのゲームですが、もうひとつの有名なアドベンチャーゲームとしてレイトン教授があります。ME Yeah, I played the very first one. And, you re probably aware that the puzzles themselves are based on a much older book series in Japan called Mental Gymnastics. I never found just doing the puzzles themselves all that engaging, but I m just amazed that they were able to fit them into this story and make it interesting. It s good that it brings these types of puzzles to a wider audience.江城:ええ、第1作目はプレイしました。そして、パズル自体は思考型パズルと日本で呼ばれているものに似ていることにおそらく気がついたでしょう。私はパズル自体にはさほど興味がありませんでしたが、それをストーリーにうまく組み込んで面白くしていることに驚きました。多くの人々にこの種のパズルを体験してもらうことは良いことです。1UP Obviously, he s in the title, so Miles Edgeworth is this game s central character. After bringing in a new protagonist for the previous game, Apollo Justice, what made you decide to bring back this character as opposed to using someone new?1UP:タイトル(Ace Attorney Investigations Miles Edgeworth)通り、御剣怜侍がこのゲームの主役であることは明白です。前作で新主人公(王泥喜)を登場させたのに、他のキャラクターに戻すことを決めたのは?ME Well, we wanted to make a new game with new skills like logic and deduction, things like that. But we took a look at the character rankings in Japan and, next to Phoenix Wright, the next most popular character was Edgeworth. He s really quite popular, and so we thought that made him a good choice as the central character for this game.江城:私たちは論理と推論に基づく新しいゲームを創りたかったのです。日本での人気キャラクターを見ると、成歩堂の次に最も人気があるのは御剣でした。彼は本当に人気があります。そのため、このゲームでは、彼を主役にするのが良いと考えました。1UP Was there anything you and the team wanted to do with the game that you just weren t able to, because of time constraints or other technical hurdles?1UP:時間的制約や、技術的な問題で、あなたや開発チームができなかったことは?ME Actually, one of the things that the director and I had talked about was the Little Thief system. We d wanted to add a lot more features -- to make a bit more in-depth. But we just ran out of time and weren t able to integrate it as fully as we d wanted to. It s little more simplistic than we d originally envisioned, but that was just a problem with time.江城:実は、ディレクターと私が話し合っていたものの1つに、「ちょっとした泥棒システム」がありました。私たちはもっと多くの特徴を加えたかったのです――徹底的に。しかし、開発期間の問題で、完全にそれらを作ることができませんでした。元々私たちが想像していたものより多少安易ではありませんが、結局は時間の問題でした。1UP Is there anything you feel you ve learned from Ace Attorney Investigations that you ve been able to apply to your current project, Okamiden?1UP:逆転検事から学んだことが、あなたの今のプロジェクトである大神伝に生かされていますか?ME Well, I m also the producer on Okamiden, so the role itself is very similar. Ace Attorney was my first solo job as a producer, so a lot about learning games promotion, the timing of releasing information, keeping players interested. Various things like that about how to promote a game.江城:大神伝ではまたプロデューサーなので、役割そのものはとても似ています。逆転裁判は私の最初のソロでのプロデューサー活動で、ゲームのプロモーション、発売情報のタイミング、プレイヤーに興味をもってもらうことなど、様々なことを学びました。But a real learning moment came when we put together the first build of Investigations. We went around showing the game to the company, and we actually got a lot of negative reactions. So, we had to go back to the drawing board and do a lot of rethinking, redesigning, reconceptualizing.しかし、捜査方法の最初の構築をした時が、本当に学べた瞬間でした。私たちが会社にゲームを見せても、ネガティブな反応ばかりでした。私たちは制作に戻らなければならず、再考し、設計し直し、コンセプトを見直さなければなりませんでした。Talking with the director, we had to think about who Edgeworth is as a character. We realized that he s actually very logical. Originally the game was simply about visiting crime scenes and investigating, but when we instituted the Logic mechanic, that changed how the game plays completely.ディレクターと、御剣というキャラについて話し合いました。私たちは、彼が非常に論理的であると考えました。当初、ゲームは単に犯行現場を訪れ、調査するだけでした。しかし、ロジックシステムを考え出した時、ゲームの方向性は変わりました。1UP Did you ever consider brining the series over to another platform besides DS?1UP:シリーズをDS以外で発売することについては?ME From the beginning, we knew this would be a DS game. The previous games were all on DS, and there s just a natural flow to continue with DS. We never really considered trying it on any other system.江城:最初から、DSのゲームを創ることを考えていました。前作までは全てDSだったので、それが自然な流れでした。私たちは他のハードでの発売を全く考えませんでした。1UP Have you felt limited at all by the DS? With Nintendo iterating on its handheld so frequently, is there any functionality that you wish it would add to the system that you think would be great to use in a game?1UP:DSによって制限されることはありませんでしたか? 任天堂はしばしば携帯ゲーム機を出していますが、ゲームに使うためのシステムを加えて欲しいと思うことは?ME I m really not the type of person to think, Oh, I wish they had this, I wish they had that. I look at it realistically, I look at the specs. Then I think, What can we do with this? What kind of fun game can we create to take advantage of this machine the most? 江城:私は「これがあればいいのに、あれがあればいいのに」というタイプではありません。スペックを見て、考えます。「これをどうできるだろうか? このハードでどんな楽しいゲームを作れるだろうか?」I guess it goes back to my roots as a programmer, but I really would just want the system to have more memory, maybe a better video card. Stuff like that. Something so we can make the best looking game possible. It s not the most wishful thinking perhaps, but that s the way I look at it.私は、それがプログラマーとしての私のルーツに戻ると思います。ただ、より多くの容量、良いビデオカードがあれば良いとは思います。より良いものを作るために。1UP Going back to your roots, you ve held so many different positions in the industry, are there any moments in particular that stand out for you? What roles did you most enjoy?1UP:ゲーム業界で色々と異なるポジションを体験してきて、特に卓越していることは? どんな仕事が楽しかったですか?ME Starting out as a programmer for Capcom, it really was fun to be able to realize a planner s vision. A planner would come up to me and say, Here are the game s rules, or, Here are the designs. And it would be up to me to put it together and make it appear on the screen. That was really great, to immediately see these ideas take fruit and know that you re the one who brought these ideas to life.江城:カプコンではプログラマーとしてスタートして、それにはプランナーとしての展望を認識できる楽しさがありました。プランナーは「これがゲームのルールだ」とか、「これがデザインだ」と言ってきます。それらをまとめるのは私次第で、ディスプレイに映し出すことができます。それは面白いことでした。As a director, it s tough to be head of a team because you then take on responsibility for everything that the team does and all the decisions. If you decide to take the game in one direction instead of another, you have to live with those consequences. It s heavy and hard, but it s also good because you have a lot more influence over the game; you can put in things you want to put in. Of course it s not 100% about what you want. It s also about listening to the ideas and opinions of your team and being able to take all those ideas and make it into one solid game. Having everything come together, the realization of those things makes it all worth it.ディレクターとしては、チームの全ての責任と決定を引き受けるので、大変なことです。もしゲームの方向性を変えるなら、その結果に耐えなくてはなりません。それは重く、厳しいです。しかし、それはまた、ゲームに良い影響を与えることにもなります。もちろん、期待していたことの100%がかなうわけではないのですが。それはまた、チームの考えや意見を聞いて、決定し、ひとつの凄いゲームが出来ることでもあります。これらの実現は素晴らしい価値があります。Being a producer is a double-edged sword. It s hard, but it s a very enjoyable at the same time. You get to stand in a different position from the director, and you get to watch a game grow from the first drafts to the very end. It s interesting to be able to manage and oversee everything in that respect. And being able to promote the game, getting out to the various media outlets is a lot of fun too. Learning how to excite people about your particular title. It s trying, but very compelling at the same time.プロデューサーであることは、諸刃の剣です。大変でもあり、楽しくもあります。ディレクターとは異なる立ち位置になり、ゲームが最初の草案から、完成まで成長していくのを見ていくことになります。その点で、全てを管理し、監督していくことは面白いです。そして、ゲームの広告や、色々なメディアに出演することは、楽しみでもあります。自分の作っているものを人々に喜んでもらう方法を学ぶこと。それは挑戦的で、同時に魅力的でもあります。1UP I know you don t control marketing in America directly, but the Ace Attorney series in particular has always had wonderful pre-order bonueses for Japan in the past. But when those same games come Stateside, it s usually without as much fanfare and with just the standalone software. Since you ve been working on the past few titles directly, how do you think the company s approach has changed with each title?1UP:私はあなたがアメリカで直接販売管理をしないということは知っていますが、逆転シリーズは過去、日本で素晴らしい予約特典がありました。しかしアメリカではそれがありません。過去直接少しのタイトルに関わり、あなたは、会社がどのように各ゲームの広告方法を変更したのだと思いますか?ME We ve definitely made some changes in how we promote things overseas versus in Japan. For example, in Japan we focus mainly on interviews with the regular press outlets like Famitsu. But in the West, we ve found going directly to the community has been very important. For Ace Attorney, we recently did a live Q A over the Capcom UStream page. It s something that s always changing, and we definitely don t have the perfect formula right now, but we re always listening to the community.江城:確かに、私たちが日本で発売したものを海外で宣伝する場合、多少方法が変わりました。例えば、日本では、宣伝するには私たちはファミ通のようなプレスの発表で、主にインタビューに集中しています。しかし海外では、私たちは、直接コミュニティで呼びかけることが重要であることがわかりました。逆転シリーズのために、私たちはカプコンのUStreamでQ Aをライブで行いました。常に色々なことが変化しています。今私たちは完全な方法というものを持ちませんが、常にコミュニティを開いています。1UP Do you think there are any particular differences between fans of the Ace Attorney series in the East and the West?1UP:日本と海外では、ファンに違いがあると思いますか?ME Actually, I went to ComicCon last year, and it was really great to see so many of our American fans in person. I don t think there s a difference between the two, or between any other countries in that respect; everyone who enjoys the games seems to enjoy them for the same reasons.江城:去年ComicConに行って、直接アメリカのファンに会えたことは、とても素晴らしいことでした。私は、国の間で違いがあるとは思いません。誰もが、同じ理由でゲームを楽しんでいるのです。1UP Well, thank you so much for taking the time to come out and talk with us. We know a lot of fans out there are eagerly awaiting the next game s release later this month.1UP:ありがとうございました。海外ファンは、今月の発売を熱心に待っています。ME Thank you very much.江城:ありがとう。 ▲ページ上へ▲
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【Tags Miku samfree tE E】 Original Music title Euthanasia Romaji music title Euthanasia Music Lyrics written, Voice edited by samfree Music arranged by samfree Singer(s) 初音ミク (Hatsune Miku) Click here for the original Japanese Lyrics English Lyrics (translated by animeyay): Drops of tears fell silently and disappeared into the ripples. Enveloped by the tides of my sentiments, I closed my eyes. Softly drinking down the sweet and bitter poison, I begin falling and falling into an eternal slumber. There is one end for me that's transient and gentle Euthanasia. Within the ripped space of time, we'll probably let go of our held hands, and the wreckage of my sentiments will eventually return to earth. Softly released towards the loneliness named "freedom", I begin falling and falling into an eternal slumber. There is one end for me that's more cruel than anything else Euthanasia. Ever since you had brought me out from bottomless darkness, I always held onto your hand, without letting go even once. That, must be an unforgivable sin. Now madness won't stop ringing in my head. I begin falling and falling into an eternal slumber. There is one end for me that's transient and gentle Euthanasia. Euthanasia... Romaji lyrics (transliterated by animeyay): seijaku ni ochita shizuku wa hamon o egaki kieta kanshou no sazanami ni dakare watashi wa me o tojita amakute nigai dokuyaku o sotto nomihoshite towa no nemuri e ochite yuku ochite yuku hitotsu no owari hakanakute yasashii Euthanasia hokorobita jikan no naka de tsunaida yubi mo hanare kanshou no zangai wa yagate tsuchi e to kaeru deshou jiyuu to iu na no kodoku e sotto hanatarete towa no nemuri e ochite yuku ochite yuku hitotsu no owari nani yori mo zankoku na Euthanasia fukai yami kara watashi o tsuredashita sono te o zutto hanasezu ni ita sore wa kitto yurusarenu tsumi nariyamanai La folia towa no nemuri e ochite yuku ochite yuku hitotsu no owari hakanakute yasashii Euthanasia Euthanasia... []
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